Remodeling of the Homer-Shank interactome may mediate homeostatic plasticity

Neurons maintain stable levels of excitability using homeostatic synaptic scaling, which adjusts the strength of a neuron’s postsynaptic inputs to compensate for extended changes in overall activity. Here, we investigated whether prolonged changes in activity affect network-level protein interaction...

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Udgivet i:Sci Signal
Main Authors: Heavner, Whitney E., Lautz, Jonathan D., Speed, Haley E., Gniffke, Edward P., Immendorf, Karen B., Welsh, John P., Baertsch, Nathan A., Smith, Stephen E.P.
Format: Artigo
Sprog:Inglês
Udgivet: 2021
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Article
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC8300860/
https://ncbi.nlm.nih.gov/pubmed/33947797
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1126/scisignal.abd7325
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