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Self-organization of stem cells into embryos: A window on early mammalian development

Embryonic development is orchestrated by robust and complex regulatory mechanisms acting at different scales of organization. In vivo studies are particularly challenging for mammals after implantation, owing to the small size and inaccessibility of the embryo. The generation of stem cell models of...

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Détails bibliographiques
Publié dans:Science
Auteurs principaux: Shahbazi, Marta N., Siggia, Eric D., Zernicka-Goetz, Magdalena
Format: Artigo
Langue:Inglês
Publié: 2019
Sujets:
Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC8300856/
https://ncbi.nlm.nih.gov/pubmed/31171690
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1126/science.aax0164
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