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Machinery, regulation and pathophysiological implications of autophagosome maturation

Autophagy is a versatile degradation system for maintaining cellular homeostasis whereby cytosolic materials are sequestered in a double-membrane autophagosome and subsequently delivered to lysosomes, where they are broken down. In multicellular organisms, newly formed autophagosomes undergo a proce...

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Detalhes bibliográficos
Publicado no:Nat Rev Mol Cell Biol
Main Authors: Zhao, Yan G., Codogno, Patrice, Zhang, Hong
Formato: Artigo
Idioma:Inglês
Publicado em: Nature Publishing Group UK 2021
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC8300085/
https://ncbi.nlm.nih.gov/pubmed/34302147
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41580-021-00392-4
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