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CD146/Soluble CD146 Pathway Is a Novel Biomarker of Angiogenesis and Inflammation in Proliferative Diabetic Retinopathy

PURPOSE: Inflammation, angiogenesis and fibrosis are pathological hallmarks of proliferative diabetic retinopathy (PDR). The CD146/sCD146 pathway displays proinflammatory and proangiogenic properties. We investigated the role of this pathway in the pathophysiology of PDR. METHODS: Vitreous samples f...

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Detalhes bibliográficos
Publicado no:Invest Ophthalmol Vis Sci
Main Authors: Abu El-Asrar, Ahmed M., Nawaz, Mohd Imtiaz, Ahmad, Ajmal, Siddiquei, Mohammad Mairaj, Allegaert, Eef, Gikandi, Priscilla W., De Hertogh, Gert, Opdenakker, Ghislain
Formato: Artigo
Idioma:Inglês
Publicado em: The Association for Research in Vision and Ophthalmology 2021
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC8300056/
https://ncbi.nlm.nih.gov/pubmed/34293080
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1167/iovs.62.9.32
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