Safety and Pharmacokinetic Profiles of Long-Acting Injectable Antiretroviral Drugs for HIV-1 Pre-Exposure Prophylaxis: A Systematic Review and Meta-analysis of Randomized Trials

Objectives: To investigate the safety and pharmacokinetic profiles of long-acting injectable pre-exposure prophylaxis (LAI PrEP), notably cabotegravir (CAB-LA) and rilpivirine (RPV-LA), for the prevention of human immunodeficiency virus-1 (HIV-1) infection. Methods: Eligible randomized trials of LAI...

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Detalhes bibliográficos
Publicado no:Front Pharmacol
Main Authors: Lazarus, Gilbert, Wangsaputra, Vincent Kharisma, Christianto, Louisa, Melva, Soetikno, Vivian, Hamers, Raph L.
Formato: Artigo
Idioma:Inglês
Publicado em: Frontiers Media S.A. 2021
Assuntos:
Pharmacology
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC8299834/
https://ncbi.nlm.nih.gov/pubmed/34305587
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3389/fphar.2021.664875
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