Rewarding Subjective Effects of the NMDAR Antagonist Nitrous Oxide (Laughing Gas) Are Moderated by Impulsivity and Depressive Symptoms in Healthy Volunteers

BACKGROUND: Nitrous oxide (N(2)O) is an anesthetic gas with both therapeutic and abuse potential. Because N(2)O is an NMDA receptor (NMDAR) antagonist, its effects are expected to resemble those of the prototypical NMDAR antagonist, ketamine. In this study, we examined the subjective rewarding effec...

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Vydáno v:Int J Neuropsychopharmacol
Hlavní autoři: Kamboj, Sunjeev K, Zhao, Hannah, Troebinger, Luzia, Piazza, Giulia, Cawley, Emma, Hennessy, Vanessa, Iskandar, Georges, Das, Ravi K
Médium: Artigo
Jazyk:Inglês
Vydáno: Oxford University Press 2021
Témata:
Regular Research Articles
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC8299821/
https://ncbi.nlm.nih.gov/pubmed/33667308
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/ijnp/pyab009
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