Global Transcriptomics Uncovers Distinct Contributions From Splicing Regulatory Proteins to the Macrophage Innate Immune Response

Pathogen sensing via pattern recognition receptors triggers massive reprogramming of macrophage gene expression. While the signaling cascades and transcription factors that activate these responses are well-known, the role of post-transcriptional RNA processing in modulating innate immune gene expre...

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Pubblicato in:Front Immunol
Autori principali: Wagner, Allison R., Scott, Haley M., West, Kelsi O., Vail, Krystal J., Fitzsimons, Timothy C., Coleman, Aja K., Carter, Kaitlyn E., Watson, Robert O., Patrick, Kristin L.
Natura: Artigo
Lingua:Inglês
Pubblicazione: Frontiers Media S.A. 2021
Soggetti:
Immunology
Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC8299563/
https://ncbi.nlm.nih.gov/pubmed/34305890
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3389/fimmu.2021.656885
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