Blockage of Drp1 phosphorylation at Ser579 protects neurons against Aβ(1–42)-induced degeneration

Alzheimer's disease (AD), one of the most common types of chronic neurodegenerative diseases, is pathologically characterized by the formation of amyloid β (Aβ) peptide-containing plaques and neurofibrillary tangles. Among Aβ peptides, Aβ(1–42) induces neuronal toxicity and neurodegeneration. I...

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Publicado en:Mol Med Rep
Main Authors: Xu, Dan, Yang, Ping, Yang, Zhang-Jian, Li, Qiu-Gen, Ouyang, Ye-Tong, Yu, Ting, Shangguan, Jian-Hui, Wan, Yu-Ying, Jiang, Li-Ping, Qu, Xin-Hui, Han, Xiao-Jian
Formato: Artigo
Idioma:Inglês
Publicado: D.A. Spandidos 2021
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Articles
Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC8299198/
https://ncbi.nlm.nih.gov/pubmed/34278489
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3892/mmr.2021.12296
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