CMIP interacts with WT1 and targets it on the proteasome degradation pathway

BACKGROUND: The Wilms tumor 1 suppressor gene, WT1, is expressed throughout life in podocytes and is essential for their function. Downregulation of WT1 has been reported in podocyte diseases but the underlying mechanisms remain unclear. Podocyte injury is the hallmark of idiopathic nephrotic syndro...

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Shranjeno v:
Bibliografske podrobnosti
izdano v:Clin Transl Med
Main Authors: Zhang, Shao‐Yu, Fan, Qingfeng, Moktefi, Anissa, Ory, Virginie, Audard, Vincent, Pawlak, Andre, Ollero, Mario, Sahali, Dil, Henique, Carole
Format: Artigo
Jezik:Inglês
Izdano: John Wiley and Sons Inc. 2021
Teme:
Research Articles
Online dostop:https://ncbi.nlm.nih.gov/pmc/articles/PMC8299046/
https://ncbi.nlm.nih.gov/pubmed/34323419
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/ctm2.460
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