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Polygenic risk modeling with latent trait-related genetic components
Polygenic risk models have led to significant advances in understanding complex diseases and their clinical presentation. While polygenic risk scores (PRS) can effectively predict outcomes, they do not generally account for disease subtypes or pathways which underlie within-trait diversity. Here, we...
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| Udgivet i: | Eur J Hum Genet |
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| Main Authors: | , , , , , |
| Format: | Artigo |
| Sprog: | Inglês |
| Udgivet: |
Springer International Publishing
2021
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| Fag: | |
| Online adgang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC8298449/ https://ncbi.nlm.nih.gov/pubmed/33558700 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41431-021-00813-0 |
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