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Transcriptional-regulatory convergence across functional MDD risk variants identified by massively parallel reporter assays

Family and population studies indicate clear heritability of major depressive disorder (MDD), though its underlying biology remains unclear. The majority of single-nucleotide polymorphism (SNP) linkage blocks associated with MDD by genome-wide association studies (GWASes) are believed to alter trans...

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Bibliografiske detaljer
Udgivet i:Transl Psychiatry
Main Authors: Mulvey, Bernard, Dougherty, Joseph D.
Format: Artigo
Sprog:Inglês
Udgivet: Nature Publishing Group UK 2021
Fag:
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC8298436/
https://ncbi.nlm.nih.gov/pubmed/34294677
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41398-021-01493-6
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