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CD73 expression in normal, hyperplastic, and neoplastic thyroid: a systematic evaluation revealing CD73 overexpression as a feature of papillary carcinomas

CD73 converts AMP to adenosine, an immunosuppressive metabolite that promotes tumorigenesis. This study presents a systematic evaluation of CD73 expression in benign, hyperplastic, and neoplastic thyroid. CD73 expression was assessed by immunohistochemistry in 142 thyroid samples. CD73 was expressed...

Ausführliche Beschreibung

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Bibliographische Detailangaben
Veröffentlicht in:Virchows Arch
Hauptverfasser: Monteiro, Inês, Missiaglia, Edoardo, Sciarra, Amedeo, Santos, João Vasco, Bouilly, Justine, Romero, Pedro, Sempoux, Christine, de Leval, Laurence
Format: Artigo
Sprache:Inglês
Veröffentlicht: Springer Berlin Heidelberg 2021
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Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC8298324/
https://ncbi.nlm.nih.gov/pubmed/34019179
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1007/s00428-021-03100-x
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