Abundant intratumoral fibrosis prevents lymphocyte infiltration into peritoneal metastases of colorectal cancer

BACKGROUND: Tumor-infiltrating lymphocytes (TILs) have been reported to reflect the anti-tumor immune status. However, recent investigations have demonstrated that intratumoral fibrosis is important as a factor affecting the infiltration of TILs. This study investigated the organ specificities of TI...

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Udgivet i:PLoS One
Main Authors: Wang, En, Shibutani, Masatsune, Nagahara, Hisashi, Fukuoka, Tatsunari, Iseki, Yasuhito, Okazaki, Yuki, Kashiwagi, Shinichiro, Tanaka, Hiroaki, Maeda, Kiyoshi, Hirakawa, Kosei, Ohira, Masaichi
Format: Artigo
Sprog:Inglês
Udgivet: Public Library of Science 2021
Fag:
Research Article
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC8297902/
https://ncbi.nlm.nih.gov/pubmed/34293030
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0255049
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