Inhibition of Aurora kinase A activity enhances the antitumor response of beta- catenin blockade in human adrenocortical cancer cells

Adrenocortical cancer (ACC) is a rare and aggressive type of endocrine tumor with high risk of recurrence and metastasis. The overall survival of patients diagnosed with ACC is low and treatment for metastatic stages remain limited to mitotane, which has low efficiency in advanced stages of the dise...

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Enregistré dans:
Détails bibliographiques
Publié dans:Mol Cell Endocrinol
Auteurs principaux: Maria, Andrea Gutierrez, Borges, Kleiton Silva, Lira, Régia Caroline Peixoto, Thomé, Carolina Hassib, Berthon, Annabel, Drougat, Ludivine, Kiseljak-Vassiliades, Katja, Wierman, Margaret E, Faucz, Fabio R., Faça, Vitor Marcel, Tone, Luiz Gonzaga, Stratakis, Constantine A.
Format: Artigo
Langue:Inglês
Publié: 2021
Sujets:
Article
Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC8297658/
https://ncbi.nlm.nih.gov/pubmed/33716050
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.mce.2021.111243
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