Intracellular activation of bioorthogonal nanozymes through endosomal proteolysis of the protein corona

Bioorthogonal activation of prodrugs provides a strategy for on-demand on-site production of therapeutics. Intracellular activation provides a strategy to localize therapeutics, potentially minimizing off-target effects. To this end, nanoparticles embedded with transition metal catalysts (nanozymes)...

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Detaylı Bibliyografya
Yayımlandı:ACS Nano
Asıl Yazarlar: Zhang, Xianzhi, Liu, Yuanchang, Gopalakrishnan, Sanjana, Castellanos-Garcia, Laura, Li, Gengtan, Malassiné, Morgane, Uddin, Imad, Huang, Rui, Luther, David C., Vachet, Richard W., Rotello, Vincent M.
Materyal Türü: Artigo
Dil:Inglês
Baskı/Yayın Bilgisi: 2020
Konular:
Article
Online Erişim:https://ncbi.nlm.nih.gov/pmc/articles/PMC8297610/
https://ncbi.nlm.nih.gov/pubmed/32227914
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/acsnano.0c00629
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