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DING Protein Inhibits Transcription of HIV-1 Gene through Suppression of Phosphorylation of NF-κB p65

INTRODUCTION: Novel plant DING proteins (full-length 38 kDa p38SJ, and 27 kDa p27SJ) exhibit phosphatase activity and modulate HIV-1 gene transcription. Previously, we demonstrated that DING regulates HIV-1 gene transcription by dephosphorylation and inactivation of CTD RNA polymerase II, the major...

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Bibliografiske detaljer
Udgivet i:J HIV AIDS
Main Authors: Darbinian, Nune, Darbinyan, Armine, Merabova, Nana, Gomberg, Rebeccah, Chabriere, Erik, Simm, Malgorzata, Selzer, Michael E, Amini, Shohreh
Format: Artigo
Sprog:Inglês
Udgivet: 2020
Fag:
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC8296972/
https://ncbi.nlm.nih.gov/pubmed/34307877
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.16966/2380-5536.175
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