Synthesis and Biological Evaluation of Fingolimod Derivatives as Antibacterial Agents

[Image: see text] We recently identified fingolimod as a potent antibiofilm compound by screening FDA-approved drugs. To study if the antibacterial activity of fingolimod could be further improved and to explore in-depth structure–activity relationships, we synthesized 28 novel fingolimod derivative...

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Библиографические подробности
Опубликовано в: :ACS Omega
Главные авторы: Zore, Matej, Gilbert-Girard, Shella, Reigada, Inés, Patel, Jayendra Z., Savijoki, Kirsi, Fallarero, Adyary, Yli-Kauhaluoma, Jari
Формат: Artigo
Язык:Inglês
Опубликовано: American Chemical Society 2021
Online-ссылка:https://ncbi.nlm.nih.gov/pmc/articles/PMC8296573/
https://ncbi.nlm.nih.gov/pubmed/34308078
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/acsomega.1c02591
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