Genomics and transcriptomics yields a system-level view of the biology of the pathogen Naegleria fowleri

BACKGROUND: The opportunistic pathogen Naegleria fowleri establishes infection in the human brain, killing almost invariably within 2 weeks. The amoeba performs piece-meal ingestion, or trogocytosis, of brain material causing direct tissue damage and massive inflammation. The cellular basis distingu...

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Udgivet i:BMC Biol
Main Authors: Herman, Emily K., Greninger, Alex, van der Giezen, Mark, Ginger, Michael L., Ramirez-Macias, Inmaculada, Miller, Haylea C., Morgan, Matthew J., Tsaousis, Anastasios D., Velle, Katrina, Vargová, Romana, Záhonová, Kristína, Najle, Sebastian Rodrigo, MacIntyre, Georgina, Muller, Norbert, Wittwer, Mattias, Zysset-Burri, Denise C., Eliáš, Marek, Slamovits, Claudio H., Weirauch, Matthew T., Fritz-Laylin, Lillian, Marciano-Cabral, Francine, Puzon, Geoffrey J., Walsh, Tom, Chiu, Charles, Dacks, Joel B.
Format: Artigo
Sprog:Inglês
Udgivet: BioMed Central 2021
Fag:
Research Article
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC8296547/
https://ncbi.nlm.nih.gov/pubmed/34294116
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s12915-021-01078-1
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