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Interleukin-27 promotes autophagy in human serum-induced primary macrophages via an mTOR- and LC3-independent pathway

Interleukin-27 (IL-27) is a cytokine that suppresses human immunodeficiency virus (HIV)-1 infection in macrophages and is considered as an immunotherapeutic reagent for infectious diseases. It is reported that IL-27 suppresses autophagy in Mycobacterium tuberculosis-infected macrophages; however, a...

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Détails bibliographiques
Publié dans:Sci Rep
Auteurs principaux: Laverdure, Sylvain, Wang, Ziqiu, Yang, Jun, Yamamoto, Takuya, Thomas, Tima, Sato, Toyotaka, Nagashima, Kunio, Imamichi, Tomozumi
Format: Artigo
Langue:Inglês
Publié: Nature Publishing Group UK 2021
Sujets:
Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC8295388/
https://ncbi.nlm.nih.gov/pubmed/34290273
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41598-021-94061-3
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