Preoperative clinical and tumor genomic features associated with pathologic lymph node metastasis in clinical stage I and II lung adenocarcinoma

While next-generation sequencing (NGS) is used to guide therapy in patients with metastatic lung adenocarcinoma (LUAD), use of NGS to determine pathologic LN metastasis prior to surgery has not been assessed. To bridge this knowledge gap, we performed NGS using MSK-IMPACT in 426 treatment-naive pati...

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Veröffentlicht in:NPJ Precis Oncol
Hauptverfasser: Caso, Raul, Connolly, James G., Zhou, Jian, Tan, Kay See, Choi, James J., Jones, Gregory D., Mastrogiacomo, Brooke, Sanchez-Vega, Francisco, Nguyen, Bastien, Rocco, Gaetano, Molena, Daniela, Sihag, Smita, Adusumilli, Prasad S., Bott, Matthew J., Jones, David R.
Format: Artigo
Sprache:Inglês
Veröffentlicht: Nature Publishing Group UK 2021
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Article
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC8295366/
https://ncbi.nlm.nih.gov/pubmed/34290393
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41698-021-00210-2
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