Roles for B[a]P and FICZ in subchondral bone metabolism and experimental temporomandibular joint osteoarthritis via the AhR/Cyp1a1 signaling axis

Bone loss due to smoking represents a major risk factor for fractures and bone osteoporosis. Signaling through the aryl hydrocarbon receptor (AhR) and its ligands contributes to both bone homeostasis and inflammatory diseases. It remains unclear whether the same AhR signaling axis affects the tempor...

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Veröffentlicht in:Sci Rep
Hauptverfasser: Yoshikawa, Yuri, Izawa, Takashi, Hamada, Yusaku, Takenaga, Hiroko, Wang, Ziyi, Ishimaru, Naozumi, Kamioka, Hiroshi
Format: Artigo
Sprache:Inglês
Veröffentlicht: Nature Publishing Group UK 2021
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Article
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC8295293/
https://ncbi.nlm.nih.gov/pubmed/34290363
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41598-021-94470-4
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