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Targeting the latent human cytomegalovirus reservoir for T-cell-mediated killing with virus-specific nanobodies

Latent human cytomegalovirus (HCMV) infection is characterized by limited gene expression, making latent HCMV infections refractory to current treatments targeting viral replication. However, reactivation of latent HCMV in immunosuppressed solid organ and stem cell transplant patients often results...

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Detalhes bibliográficos
Publicado no:Nat Commun
Main Authors: De Groof, Timo W. M., Elder, Elizabeth G., Lim, Eleanor Y., Heukers, Raimond, Bergkamp, Nick D., Groves, Ian J., Wills, Mark, Sinclair, John H., Smit, Martine J.
Formato: Artigo
Idioma:Inglês
Publicado em: Nature Publishing Group UK 2021
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC8295288/
https://ncbi.nlm.nih.gov/pubmed/34290252
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41467-021-24608-5
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