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A hypothesis for the pathogenesis of radiation-induced oral mucositis: when biological challenges exceed physiologic protective mechanisms. Implications for pharmacological prevention and treatment

Oral mucositis (OM) remains a significant unmet need for patients being treated with standard concomitant chemoradiation (CRT) regimens for head and neck cancers (HNC). OM’s pathogenesis is complex and includes both direct and indirect damage pathways. In this paper, the field is reviewed with empha...

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Dettagli Bibliografici
Pubblicato in:Support Care Cancer
Autore principale: Sonis, Stephen T.
Natura: Artigo
Lingua:Inglês
Pubblicazione: Springer Berlin Heidelberg 2021
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Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC8295245/
https://ncbi.nlm.nih.gov/pubmed/33712912
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1007/s00520-021-06108-w
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