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Niacin increases atherogenic proteins in HDL of statin-treated subjects

OBJECTIVE –: Niacin therapy fails to reduce cardiovascular events in statin-treated subjects even though it increases plasma HDL cholesterol (HDL-C) and decreases LDL-C and triglyceride levels. To investigate potential mechanisms for this lack of cardioprotection, we quantified the HDL proteome of s...

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Detalhes bibliográficos
Publicado no:Arterioscler Thromb Vasc Biol
Main Authors: Ronsein, Graziella E., Vaisar, Tomas, Davidson, W. Sean, Bornfeldt, Karin E., Probstfield, Jeffrey L., O’Brien, Kevin D., Zhao, Xue-Qiao, Heinecke, Jay W.
Formato: Artigo
Idioma:Inglês
Publicado em: 2021
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC8295224/
https://ncbi.nlm.nih.gov/pubmed/34134520
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1161/ATVBAHA.121.316278
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