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Cytoplasmic ADP-ribosylation levels correlate with markers of patient outcome in distinct human cancers

ADP-ribosylation (ADPR) is a posttranslational modification whose importance in oncology keeps increasing due to frequent use of PARP inhibitors (PARPi) to treat different tumor types. Due to the lack of suitable tools to analyze cellular ADPR levels, ADPR’s significance for cancer progression and p...

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Detalhes bibliográficos
Publicado no:Mod Pathol
Main Authors: Aimi, Fabio, Moch, Holger, Schraml, Peter, Hottiger, Michael O.
Formato: Artigo
Idioma:Inglês
Publicado em: Nature Publishing Group US 2021
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC8295037/
https://ncbi.nlm.nih.gov/pubmed/33742140
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41379-021-00788-9
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