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A facile chemoenzymatic synthesis of SARS-CoV-2 glycopeptides for probing glycosylation functions

Glycosylation plays important roles in SARS-CoV-2 infection. We describe here a facile chemoenzymatic synthesis of core-fucosylated N-glycopeptides derived from the SARS-CoV-2 Spike protein and their binding with glycan-dependent neutralizing antibody S309 and human lectin CLEC4G. The synthetic glyc...

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Detalhes bibliográficos
Publicado no:Chem Commun (Camb)
Main Authors: Zong, Guanghui, Li, Chao, Prabhu, Sunaina Kiran, Zhang, Roushu, Zhang, Xiao, Wang, Lai-Xi
Formato: Artigo
Idioma:Inglês
Publicado em: 2021
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC8294178/
https://ncbi.nlm.nih.gov/pubmed/34236361
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1039/d1cc02790e
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