Interferon-lambda 3 and 4 Polymorphisms Increase Sustained Virological Responses and Regulate Innate Immunity in Antiviral Therapy With Pegylated Interferon-Alpha

Sustained virologic response (SVR) in chronic hepatitis C (CHC) treatment denotes that the host genetics controls the immune response and unequivocally contribute to viral clearance or disease severity. In this context, single nucleotide polymorphisms (SNPs) in the locus of interferon lambda 3 and 4...

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Udgivet i:Front Cell Infect Microbiol
Main Authors: da Silva, Andréa Marques Vieira, Alvarado-Arnez, Lucia Elena, Azamor, Tamiris, Batista-Silva, Leonardo Ribeiro, Leal-Calvo, Thyago, Bezerra, Ohanna Cavalcanti de Lima, Ribeiro-Alves, Marcelo, Kehdy, Fernanda de Souza Gomes, Neves, Patrícia Cristina da Costa, Bayma, Camilla, da Silva, Jane, de Souza, Alessandro Fonseca, Muller, Marcelo, de Andrade, Elisabete Ferreira, Andrade, Ana Carolina Magalhães, dos Santos, Eliane Matos, Xavier, Janaína Reis, Maia, Maria De Lourdes De Sousa, Meireles, Rolando Páez, Cuni, Hugo Nodarse, Sander, Guilherme Becker, Picon, Paulo Dornelles, Matos, Denise C S, Moraes, Milton Ozório
Format: Artigo
Sprog:Inglês
Udgivet: Frontiers Media S.A. 2021
Fag:
Cellular and Infection Microbiology
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC8294038/
https://ncbi.nlm.nih.gov/pubmed/34307188
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3389/fcimb.2021.656393
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