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Functional Polymorphisms in the p53 Pathway Genes on the Genetic Susceptibility to Zika Virus Teratogenesis

Congenital Zika Syndrome (CZS) occurs in up to 42% of individuals exposed to ZIKV prenatally. Deregulation in gene expression and protein levels of components of the p53 signaling pathway, such as p53 and MDM2, due to ZIKV infection has been reported. Here, we evaluate functional polymorphisms in ge...

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Publicat a:Front Cell Infect Microbiol
Autors principals: Gomes, Julia A., Sgarioni, Eduarda, Vieira, Igor A., Fraga, Lucas R., Ashton-Prolla, Patrícia, Terças-Tretell, Ana Cláudia P., da Silva, Juliana H., Ribeiro, Bethânia F.R., Galera, Marcial F., de Oliveira, Thalita M., Carvalho de Andrade, Maria Denise F., Carvalho, Isabella F., Schuler-Faccini, Lavínia, Vianna, Fernanda S. L.
Format: Artigo
Idioma:Inglês
Publicat: Frontiers Media S.A. 2021
Matèries:
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC8294037/
https://ncbi.nlm.nih.gov/pubmed/34307186
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3389/fcimb.2021.641413
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