Inflammasome-Induced Osmotic Pressure and the Mechanical Mechanisms Underlying Astrocytic Swelling and Membrane Blebbing in Pyroptosis

Cell swelling and membrane blebbing are characteristic of pyroptosis. In the present study, we explored the role of intracellular tension activity in the deformation of pyroptotic astrocytes. Protein nanoparticle-induced osmotic pressure (PN-OP) was found to be involved in cell swelling and membrane...

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Detalles Bibliográficos
Publicado en:Front Immunol
Main Authors: Zheng, Zihui, Wang, Tingting, Chen, Jiahui, Qiu, Huimin, Zhang, Chencheng, Liu, Weizhen, Qin, Simiao, Tian, Jilai, Guo, Jun
Formato: Artigo
Idioma:Inglês
Publicado: Frontiers Media S.A. 2021
Assuntos:
Immunology
Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC8293990/
https://ncbi.nlm.nih.gov/pubmed/34305921
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3389/fimmu.2021.688674
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