Blunted natriuretic response to saline loading in sheep with hypertensive kidney disease following radiofrequency catheter-based renal denervation

Renal sympathetic nerves contribute to renal excretory function during volume expansion. We hypothesized that intact renal innervation is required for excretion of a fluid/electrolyte load in hypertensive chronic kidney disease (CKD) and normotensive healthy settings. Blood pressure, kidney hemodyna...

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Veröffentlicht in:Sci Rep
Hauptverfasser: Singh, Reetu R., McArdle, Zoe, Singh, Harshil, Booth, Lindsea C., May, Clive N., Head, Geoffrey A., Moritz, Karen M., Schlaich, Markus P., Denton, Kate M.
Format: Artigo
Sprache:Inglês
Veröffentlicht: Nature Publishing Group UK 2021
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Article
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC8292431/
https://ncbi.nlm.nih.gov/pubmed/34285286
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41598-021-94221-5
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