Targeting the actin/tropomyosin cytoskeleton in epithelial ovarian cancer reveals multiple mechanisms of synergy with anti-microtubule agents

BACKGROUND: Anti-microtubule agents are widely used to treat ovarian cancers, but the efficacy is often compromised by drug resistance. We investigated co-targeting the actin/tropomyosin cytoskeleton and microtubules to increase treatment efficacy in ovarian cancers and potentially overcome resistan...

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Pubblicato in:Br J Cancer
Autori principali: Xu, Xing, Wang, Yao, Bryce, Nicole S., Tang, Katrina, Meagher, Nicola S., Kang, Eun Young, Kelemen, Linda E., Köbel, Martin, Ramus, Susan J., Friedlander, Michael, Ford, Caroline E., Hardeman, Edna C., Gunning, Peter W.
Natura: Artigo
Lingua:Inglês
Pubblicazione: Nature Publishing Group UK 2021
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Article
Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC8292367/
https://ncbi.nlm.nih.gov/pubmed/33981016
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41416-021-01420-y
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