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Correlation between Family RB1 Gene Pathogenic Variant with Clinical Features and Prognosis of Retinoblastoma under 5 Years Old

Retinoblastoma (RB) is the most common primary intraocular malignant tumor in infants and the prototype of human hereditary tumors. Its occurrence and development are closely related to the pathogenic variant of tumor suppressor RB1 gene. We aim to analyze the characteristics of RB1 gene pathogenic...

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Bibliographic Details
Published in:Dis Markers
Main Authors: Zhang, Yi, Wang, Yizhuo, Huang, Dongsheng, Ma, Jianmin, Zhang, Weiling, Gu, Huali, Zhou, Yan, Yi, You, Zhang, Pinwei
Format: Artigo
Language:Inglês
Published: Hindawi 2021
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Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC8292087/
https://ncbi.nlm.nih.gov/pubmed/34336010
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1155/2021/9981028
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