Tobacco Smoking Increases Methylation of Polypyrimidine Tract Binding Protein 1 Promoter in Intracranial Aneurysms

DNA methylation at the gene promoter region is reportedly involved in the development of intracranial aneurysm (IA). This study aims to investigate the methylation levels of polypyrimidine tract-binding protein 1 (PTBP1) in IA, as well as its potential to predict IA. Forty-eight patients with IA and...

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Опубликовано в: :Front Aging Neurosci
Главные авторы: Wang, Zhepei, Zhou, Shengjun, Zhao, Jikuang, Nie, Sheng, Sun, Jie, Gao, Xiang, Lenahan, Cameron, Lin, Zhiqin, Huang, Yi, Chen, Gao
Формат: Artigo
Язык:Inglês
Опубликовано: Frontiers Media S.A. 2021
Предметы:
Neuroscience
Online-ссылка:https://ncbi.nlm.nih.gov/pmc/articles/PMC8292010/
https://ncbi.nlm.nih.gov/pubmed/34295240
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3389/fnagi.2021.688179
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