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Trelagliptin stimulates osteoblastic differentiation by increasing runt-related transcription factor 2 (RUNX2): a therapeutic implication in osteoporosis

Osteoporosis, an aging-associated bone metabolic disease, is affecting millions of people worldwide. The deregulated process of osteoblastic differentiation has been linked with the progression of osteoporosis. Trelagliptin is a long-acting inhibitor of DPP-4 used for the management of type 2 diabet...

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Detalhes bibliográficos
Publicado no:Bioengineered
Main Authors: Shao, Haiyu, Wu, Renzheng, Cao, Li, Gu, Haifeng, Chai, Fang
Formato: Artigo
Idioma:Inglês
Publicado em: Taylor & Francis 2021
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC8291811/
https://ncbi.nlm.nih.gov/pubmed/33734011
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1080/21655979.2021.1900633
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