Transgenic expression of a T cell epitope in Strongyloides ratti reveals that helminth-specific CD4+ T cells constitute both Th2 and Treg populations

Helminths are distinct from microbial pathogens in both size and complexity, and are the likely evolutionary driving force for type 2 immunity. CD4+ helper T cells can both coordinate worm clearance and prevent immunopathology, but issues of T cell antigen specificity in the context of helminth-indu...

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Vydáno v:PLoS Pathog
Hlavní autoři: Douglas, Bonnie, Wei, Yun, Li, Xinshe, Ferguson, Annabel, Hung, Li-Yin, Pastore, Christopher, Kurtz, Jonathan R, McLachlan, James B., Nolan, Thomas J., Lok, James, Herbert, De’Broski R.
Médium: Artigo
Jazyk:Inglês
Vydáno: Public Library of Science 2021
Témata:
Research Article
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC8291758/
https://ncbi.nlm.nih.gov/pubmed/34237106
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.ppat.1009709
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