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Genomic-Led Discovery of a Novel Glycopeptide Antibiotic by Nonomuraea coxensis DSM 45129

[Image: see text] Glycopeptide antibiotics (GPAs) are last defense line drugs against multidrug-resistant Gram-positive pathogens. Natural GPAs teicoplanin and vancomycin, as well as semisynthetic oritavancin, telavancin, and dalbavancin, are currently approved for clinical use. Although these antib...

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Veröffentlicht in:ACS Chem Biol
Hauptverfasser: Yushchuk, Oleksandr, Vior, Natalia M., Andreo-Vidal, Andres, Berini, Francesca, Rückert, Christian, Busche, Tobias, Binda, Elisa, Kalinowski, Jörn, Truman, Andrew W., Marinelli, Flavia
Format: Artigo
Sprache:Inglês
Veröffentlicht: American Chemical Society 2021
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC8291499/
https://ncbi.nlm.nih.gov/pubmed/33913701
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/acschembio.1c00170
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