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Integration of Mass Spectrometry Imaging and Machine Learning Visualizes Region-Specific Age-Induced and Drug-Target Metabolic Perturbations in the Brain

[Image: see text] Detailed metabolic imaging of specific brain regions in early aging may expose pathophysiological mechanisms and indicate effective neuropharmacological targets in the onset of cognitive decline. Comprehensive imaging of brain aging and drug-target effects is restricted using conve...

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Bibliografiske detaljer
Udgivet i:ACS Chem Neurosci
Main Authors: Vallianatou, Theodosia, Shariatgorji, Reza, Nilsson, Anna, Karlgren, Maria, Hulme, Heather, Fridjonsdottir, Elva, Svenningsson, Per, Andrén, Per E.
Format: Artigo
Sprog:Inglês
Udgivet: American Chemical Society 2021
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC8291481/
https://ncbi.nlm.nih.gov/pubmed/33939923
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/acschemneuro.1c00103
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