Transgenic rhesus monkeys carrying the human MCPH1 gene copies show human-like neoteny of brain development

Brain size and cognitive skills are the most dramatically changed traits in humans during evolution and yet the genetic mechanisms underlying these human-specific changes remain elusive. Here, we successfully generated 11 transgenic rhesus monkeys (8 first-generation and 3 second-generation) carryin...

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Wedi'i Gadw mewn:
Manylion Llyfryddiaeth
Cyhoeddwyd yn:Natl Sci Rev
Prif Awduron: Shi, Lei, Luo, Xin, Jiang, Jin, Chen, Yongchang, Liu, Cirong, Hu, Ting, Li, Min, Lin, Qiang, Li, Yanjiao, Huang, Jun, Wang, Hong, Niu, Yuyu, Shi, Yundi, Styner, Martin, Wang, Jianhong, Lu, Yi, Sun, Xuejin, Yu, Hualin, Ji, Weizhi, Su, Bing
Fformat: Artigo
Iaith:Inglês
Cyhoeddwyd: Oxford University Press 2019
Pynciau:
Research Article
Mynediad Ar-lein:https://ncbi.nlm.nih.gov/pmc/articles/PMC8291473/
https://ncbi.nlm.nih.gov/pubmed/34691896
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/nsr/nwz043
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