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PARK Genes Link Mitochondrial Dysfunction and Alpha-Synuclein Pathology in Sporadic Parkinson’s Disease

Parkinson’s disease (PD) is an age-related neurodegenerative disorder affecting millions of people worldwide. The disease is characterized by the progressive loss of dopaminergic neurons and spread of Lewy pathology (α-synuclein aggregates) in the brain but the pathogenesis remains elusive. PD prese...

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Detalhes bibliográficos
Publicado no:Front Cell Dev Biol
Main Authors: Li, Wen, Fu, YuHong, Halliday, Glenda M., Sue, Carolyn M.
Formato: Artigo
Idioma:Inglês
Publicado em: Frontiers Media S.A. 2021
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC8291125/
https://ncbi.nlm.nih.gov/pubmed/34295884
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3389/fcell.2021.612476
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