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Application of TGF-β1, TIMP-1 and TIMP-2 small interfering RNAs can alleviate CCl(4)-induced hepatic fibrosis in rats by rebalancing Th1/Th2 cytokines
The present study aimed to investigate the effects of TGF-β1, tissue inhibitor of metalloproteinase (TIMP)-1 small interfering (si)RNA and TIMP-2 siRNA on hepatic fibrosis in rats and explore the T helper (Th)1/Th2 balance. Moreover, IFN-γ, IL-4 and IL-13 are the main cytokines associated with Th1/T...
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| Pubblicato in: | Exp Ther Med |
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| Autori principali: | , , , , |
| Natura: | Artigo |
| Lingua: | Inglês |
| Pubblicazione: |
D.A. Spandidos
2021
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| Soggetti: | |
| Accesso online: | https://ncbi.nlm.nih.gov/pmc/articles/PMC8290469/ https://ncbi.nlm.nih.gov/pubmed/34335905 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3892/etm.2021.10395 |
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