Cerebrospinal Fluid of Patients With Alzheimer’s Disease Contains Increased Percentages of Synaptophysin-Bearing Microvesicles

INTRODUCTION: In Alzheimer’s disease, the severity of symptoms is linked to a loss of synaptic density and the spread of pathologically hyperphosphorylated tau. The established cerebrospinal fluid markers Aβ, tau and phospho-tau reflect the histopathological hallmarks of Alzheimer’s disease but do n...

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Publicado en:Front Aging Neurosci
Autores principales: Utz, Janine, Berner, Judith, Muñoz, Luis Enrique, Oberstein, Timo Jan, Kornhuber, Johannes, Herrmann, Martin, Maler, Juan Manuel, Spitzer, Philipp
Formato: Artigo
Lenguaje:Inglês
Publicado: Frontiers Media S.A. 2021
Materias:
Neuroscience
Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC8290128/
https://ncbi.nlm.nih.gov/pubmed/34295239
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3389/fnagi.2021.682115
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