Untargeted metabolomics and transcriptomics identified glutathione metabolism disturbance and PCS and TMAO as potential biomarkers for ER stress in lung

Endoplasmic reticulum (ER) stress is a cellular state that results from the overload of unfolded/misfolded protein in the ER that, if not resolved properly, can lead to cell death. Both acute lung infections and chronic lung diseases have been found related to ER stress. Yet no study has been presen...

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Pubblicato in:Sci Rep
Autori principali: Wang, Zijing, Ma, Peng, Wang, Yisa, Hou, Biyu, Zhou, Can, Tian, He, Li, Bowen, Shui, Guanghou, Yang, Xiuying, Qiang, Guifen, Yin, Chengqian, Du, Guanhua
Natura: Artigo
Lingua:Inglês
Pubblicazione: Nature Publishing Group UK 2021
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Article
Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC8290008/
https://ncbi.nlm.nih.gov/pubmed/34282162
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41598-021-92779-8
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