Whole-genome optical mapping of bone-marrow myeloma cells reveals association of extramedullary multiple myeloma with chromosome 1 abnormalities

Extramedullary disease (EMM) represents a rare, aggressive and mostly resistant phenotype of multiple myeloma (MM). EMM is frequently associated with high-risk cytogenetics, but their complex genomic architecture is largely unexplored. We used whole-genome optical mapping (Saphyr, Bionano Genomics)...

Celý popis

Uloženo v:
Podrobná bibliografie
Vydáno v:Sci Rep
Hlavní autoři: Kriegova, Eva, Fillerova, Regina, Minarik, Jiri, Savara, Jakub, Manakova, Jirina, Petrackova, Anna, Dihel, Martin, Balcarkova, Jana, Krhovska, Petra, Pika, Tomas, Gajdos, Petr, Behalek, Marek, Vasinek, Michal, Papajik, Tomas
Médium: Artigo
Jazyk:Inglês
Vydáno: Nature Publishing Group UK 2021
Témata:
Article
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC8289962/
https://ncbi.nlm.nih.gov/pubmed/34282158
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41598-021-93835-z
Tagy: Přidat tag
Žádné tagy, Buďte první, kdo otaguje tento záznam!

Podobné jednotky