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Staphylococcal Infection Prevention using Antibiotic-loaded Mannitol-Chitosan Paste in Rabbit Model of Implant-associated Osteomyelitis

Antibiotic-loaded chitosan pastes have shown advantages in treatment and coverage of complex musculoskeletal defects. We added mannitol, previously shown to increase antibiotic susceptibility of biofilm, to an injectable chitosan/polyethylene glycol paste for delivery of antibiotics. Ground sponges...

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Detalhes bibliográficos
Publicado no:J Orthop Res
Main Authors: Harrison, Zoe L., Pace, Leslie R., Brown, Madison N., Beenken, Karen E., Smeltzer, Mark S., Bumgardner, Joel D., Haggard, Warren O., Jennings, J. Amber
Formato: Artigo
Idioma:Inglês
Publicado em: 2021
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC8289950/
https://ncbi.nlm.nih.gov/pubmed/33470467
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/jor.24986
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