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Trophoblast glycoprotein is a marker for efficient sorting of ventral mesencephalic dopaminergic precursors derived from human pluripotent stem cells

Successful cell therapy for Parkinson’s disease (PD) requires large numbers of homogeneous ventral mesencephalic dopaminergic (vmDA) precursors. Enrichment of vmDA precursors via cell sorting is required to ensure high safety and efficacy of the cell therapy. Here, using LMX1A-eGFP knock-in reporter...

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Bibliografiska uppgifter
I publikationen:NPJ Parkinsons Dis
Huvudupphovsmän: Yoo, Jeong-Eun, Lee, Dongjin R., Park, Sanghyun, Shin, Hye-Rim, Lee, Kun Gu, Kim, Dae-Sung, Jo, Mi-Young, Eom, Jang-Hyeon, Cho, Myung Soo, Hwang, Dong-Youn, Kim, Dong-Wook
Materialtyp: Artigo
Språk:Inglês
Publicerad: Nature Publishing Group UK 2021
Ämnen:
Länkar:https://ncbi.nlm.nih.gov/pmc/articles/PMC8289854/
https://ncbi.nlm.nih.gov/pubmed/34282148
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41531-021-00204-8
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