Metabolic reprogramming of T regulatory cells in the hypoxic tumor microenvironment

Metabolic dysregulation in the hypoxic tumor microenvironment (TME) is considered as a hallmark of solid tumors, leading to changes in biosynthetic pathways favoring onset, survival and proliferation of malignant cells. Within the TME, hypoxic milieu favors metabolic reprogramming of tumor cells, wh...

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Bibliographic Details
Published in:Cancer Immunol Immunother
Main Authors: Sasidharan Nair, Varun, Saleh, Reem, Toor, Salman M., Cyprian, Farhan S., Elkord, Eyad
Format: Artigo
Language:Inglês
Published: Springer Berlin Heidelberg 2021
Subjects:
Review
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC8289790/
https://ncbi.nlm.nih.gov/pubmed/33532902
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1007/s00262-020-02842-y
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