Association of NRAS Mutation With Clinical Outcomes of Anti-PD-1 Monotherapy in Advanced Melanoma: A Pooled Analysis of Four Asian Clinical Trials

BACKGROUND: Anti-PD-1 monotherapy is the standard therapy for advanced melanoma patients, including those with NRAS mutations. The influence of NRAS mutation on immunotherapy, especially in noncutaneous melanoma, is largely uncharacterized. MATERIALS AND METHODS: We analyzed clinical data of four cl...

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Detalhes bibliográficos
Publicado no:Front Immunol
Main Authors: Zhou, Li, Wang, Xuan, Chi, Zhihong, Sheng, Xinan, Kong, Yan, Mao, Lili, Lian, Bin, Tang, Bixia, Yan, Xieqiao, Bai, Xue, Li, Siming, Guo, Jun, Cui, Chuanliang, Si, Lu
Formato: Artigo
Idioma:Inglês
Publicado em: Frontiers Media S.A. 2021
Assuntos:
Immunology
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC8289467/
https://ncbi.nlm.nih.gov/pubmed/34290710
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3389/fimmu.2021.691032
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