An antipathogenic compound that targets the OxyR peroxide sensor in Pseudomonas aeruginosa

INTRODUCTION: Antipathogenic or antivirulence strategy is to target a virulence pathway that is dispensable for growth, in the hope to mitigate the selection for drug resistance. HYPOTHESIS/GAP STATMENT: Peroxide stress responses are one of the conserved virulence pathways in bacterial pathogens and...

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Pubblicato in:J Med Microbiol
Autori principali: Oh, Hyo-Young, Jalde, Shivakumar S., Chung, In-Young, Yoo, Yeon-Ji, Jang, Hye-Jeong, Choi, Hyun-Kyung, Cho, You-Hee
Natura: Artigo
Lingua:Inglês
Pubblicazione: Microbiology Society 2021
Soggetti:
Prevention, Therapy and Therapeutics
Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC8289212/
https://ncbi.nlm.nih.gov/pubmed/33830911
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1099/jmm.0.001341
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