RPS15 mutations rewire RNA translation in chronic lymphocytic leukemia

Recent studies of chronic lymphocytic leukemia (CLL) have reported recurrent mutations in the RPS15 gene, which encodes the ribosomal protein S15 (RPS15), a component of the 40S ribosomal subunit. Despite some evidence about the role of mutant RPS15 (mostly obtained from the analysis of cell lines),...

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Vydáno v:Blood Adv
Hlavní autoři: Ntoufa, Stavroula, Gerousi, Marina, Laidou, Stamatia, Psomopoulos, Fotis, Tsiolas, Georgios, Moysiadis, Theodoros, Papakonstantinou, Nikos, Mansouri, Larry, Anagnostopoulos, Achilles, Stavrogianni, Niki, Pospisilova, Sarka, Plevova, Karla, Makris, Antonios M., Rosenquist, Richard, Stamatopoulos, Kostas
Médium: Artigo
Jazyk:Inglês
Vydáno: American Society of Hematology 2021
Témata:
Lymphoid Neoplasia
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC8288675/
https://ncbi.nlm.nih.gov/pubmed/34251413
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1182/bloodadvances.2020001717
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