A single-cell transcriptomic atlas of primate pancreatic islet aging

Aging-related degeneration of pancreatic islet cells contributes to impaired glucose tolerance and diabetes. Endocrine cells age heterogeneously, complicating the efforts to unravel the molecular drivers underlying endocrine aging. To overcome these obstacles, we undertook single-cell RNA sequencing...

Disgrifiad llawn

Wedi'i Gadw mewn:
Manylion Llyfryddiaeth
Cyhoeddwyd yn:Natl Sci Rev
Prif Awduron: Li, Jingyi, Zheng, Yuxuan, Yan, Pengze, Song, Moshi, Wang, Si, Sun, Liang, Liu, Zunpeng, Ma, Shuai, Izpisua Belmonte, Juan Carlos, Chan, Piu, Zhou, Qi, Zhang, Weiqi, Liu, Guang-Hui, Tang, Fuchou, Qu, Jing
Fformat: Artigo
Iaith:Inglês
Cyhoeddwyd: Oxford University Press 2020
Pynciau:
Molecular Biology & Genetics
Mynediad Ar-lein:https://ncbi.nlm.nih.gov/pmc/articles/PMC8288398/
https://ncbi.nlm.nih.gov/pubmed/34691567
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/nsr/nwaa127
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