A single-cell transcriptomic atlas of primate pancreatic islet aging

Aging-related degeneration of pancreatic islet cells contributes to impaired glucose tolerance and diabetes. Endocrine cells age heterogeneously, complicating the efforts to unravel the molecular drivers underlying endocrine aging. To overcome these obstacles, we undertook single-cell RNA sequencing...

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Shranjeno v:
Bibliografske podrobnosti
izdano v:Natl Sci Rev
Main Authors: Li, Jingyi, Zheng, Yuxuan, Yan, Pengze, Song, Moshi, Wang, Si, Sun, Liang, Liu, Zunpeng, Ma, Shuai, Izpisua Belmonte, Juan Carlos, Chan, Piu, Zhou, Qi, Zhang, Weiqi, Liu, Guang-Hui, Tang, Fuchou, Qu, Jing
Format: Artigo
Jezik:Inglês
Izdano: Oxford University Press 2020
Teme:
Molecular Biology & Genetics
Online dostop:https://ncbi.nlm.nih.gov/pmc/articles/PMC8288398/
https://ncbi.nlm.nih.gov/pubmed/34691567
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/nsr/nwaa127
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