A single-cell transcriptomic atlas of primate pancreatic islet aging

Aging-related degeneration of pancreatic islet cells contributes to impaired glucose tolerance and diabetes. Endocrine cells age heterogeneously, complicating the efforts to unravel the molecular drivers underlying endocrine aging. To overcome these obstacles, we undertook single-cell RNA sequencing...

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Detalhes bibliográficos
Publicado no:Natl Sci Rev
Main Authors: Li, Jingyi, Zheng, Yuxuan, Yan, Pengze, Song, Moshi, Wang, Si, Sun, Liang, Liu, Zunpeng, Ma, Shuai, Izpisua Belmonte, Juan Carlos, Chan, Piu, Zhou, Qi, Zhang, Weiqi, Liu, Guang-Hui, Tang, Fuchou, Qu, Jing
Formato: Artigo
Idioma:Inglês
Publicado em: Oxford University Press 2020
Assuntos:
Molecular Biology & Genetics
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC8288398/
https://ncbi.nlm.nih.gov/pubmed/34691567
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/nsr/nwaa127
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